09 Jun Linear regression designs were used to test relationship anywhere between D l
Subjects born at between 23 and 30 weeks of gestation and having a diagnosis of BPD were recruited from the Neonatal Intensive Care Unit or the Pediatric Pulmonary Clinic of James Whitcomb Riley Hospital for Children (Indianapolis, IN) between 2008 and 2012. BPD was defined as an oxygen requirement (>21% F i O2) for at least 28 days. Subjects were clinically stable outpatients with no oxygen requirement at the time of testing and no acute respiratory symptoms for at least 3 weeks.
Victims produced during the 37 months out-of gestation otherwise later were hired using adverts within the local publications within the Indianapolis, Indiana, between 2008 and you may 2013. All the victims had no cardiorespiratory malformations, and all sorts of got a breathing record negative for wheezing, asthma, procedures having asthma medication, otherwise hospitalization getting a respiratory disease.
Subjects were evaluated between 2008 and 2013 at James Whitcomb Riley Hospital for Children while sleeping in a supine position with chloral hydrate sedation (50–100 mg/kg). Oxygen saturation and heart rate were https://datingranking.net/sugar-daddies-usa/ia/ monitored during testing as recommended in American Thoracic Society/European Respiratory Society guidelines (13). The study was approved by the institutional review board at Indiana University, and parental informed consent was obtained. D l CO values measured on room air were previously reported for 18 subjects with BPD and 25 FT infants (8, 14).